HGUE-C-1 is an atypical and novel colon carcinoma cell line

Mitomycin C resistance in a human colon carcinoma cell line associated with cell surface protein alterations.

A human colon carcinoma cell line resistant to mitomycin C (MMC) was obtained by repeated exposure of a previously described sensitive parental line, HCT 116, to MMC in vitro. Xenografts grown from the MMC-resistant phenotype were not inhibited in MMC-treated animals, while MMC treatment produced growth inhibition in parental cell xenografts. The MMC-resistant phenotype exhibited a greater amou...

Inhibition of Immune System by an Immunosuppressive Factor from a Human Prostatic Carcinoma Cell Line (JCA-1)

Prostatic carcinoma is the most commonly diagnosed tumor among men over 40 which results in over 30,000 deaths each year in the United States. Previous studies indicated that tumor cell lines produce and release several growth regulatory factors into their condition media and so far a number of human tumor cell-derived suppressor factors have been isolated that affect normal immune functions. I...

isolation and identification of putative cancer stem cells in c26 murine colon carcinoma cell line

Purines induce lipofuscin formation in a colon carcinoma cell line.

Lipofuscin was produced when HT29, a colon carcinoma cell line, was cultured in millimolar concentrations of xanthine and guanine but not in the presence of other bases. Using a simple assay developed to quantify the fluorescent pigment, it was found that maximum levels of lipofuscin were developed in 3 days. Methylxanthines that are not substrates of xanthine dehydrogenase, such as caffeine an...

Carcinoma Cell Line by Upregulating LFA-1 Tumoricidal Activity against a Colon IL-18 Is Involved in Eosinophil-Mediated